Efficacy of anti-diarrheal activity of Pedalium murex L., in wistar albino rats

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Efficacy of anti-diarrheal activity of Pedalium murex L., in wistar albino rats

Methods The ethyl acetate extract of Pedalium murex L., (250, 500, and 1000 mg/kg body weight) was administered orally to three groups of rats (five animals per group) in order to evaluate the activity of the extract against castor oil-induced diarrhea model in rat. Two other groups received normal saline (5mg/kg) and loperamide (5mg/kg) as positive control. The effect of the extract on intesti...

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EFFECT OF ETHANOLIC FRUIT EXTRACT OF Pedalium murex Linn. IN ETHYLENE GLYCOL INDUCED UROLITHIASIS IN MALE WISTAR ALBINO RATS

The ethanolic fruit extract of Pedalium murex to ethylene glycol intoxicated rats reverted the levels of the liver and kidney markers to near normal levels protecting liver and renal tissues from damage and also prevents the crystal retention in tissues. The levels of ACP, ALP, AST, ALT in serum andurine were significantly increased due to the damaged structural integrity of renal and hepatic c...

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Evaluation of Antipyretic Activity of Pedalium murex Against Brewer’s Yeast-Induced Pyrexia in Rats

The aqueous and ethanolic extracts of Pedalium murex (Pedaliaceae) was investigated for antipyretic activity in rats using Brewer’s yeast-induced pyrexia models. Brewer’s yeast (15%) was used to induce pyrexia in rats. Both the extract (200 and 400 mg/kg body weight p.o produced a significant (p

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ANTI-ULCER ACTIVITY OF ETHANOLIC EXTRACT FROM STEMS OF IPOMOEA PES- CAPRAE (L.) R.Br IN WISTAR ALBINO RATS

Ipomoea Pes-caprae(L.) R.Br (IP)distributed in the tropics and subtropics regions is used in folk and tribal medicines. Traditionally IP was used to treat arthritis, pain, ulcer, cancer and wounds. The present study aims to discover the anti-ulcer effect of ethanolic extract from stems of IP (EESIP) at doses 200 mg/kg & 400 mg/kg in aspirin and pylorus ligature induced gastric ulcer models in t...

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Comparative Evaluation of Anti-Inflammatory activity of different Extracts of Boswellia serrata in Wistar Albino Rats

Inflammation is the local response of living mammalian tissues to injury due to any agent. It is the body defence reaction in order to eliminate or limit the spread of injurious agent, followed by removel of the necrosed cells and tissues, but the sign and symptoms which are produced during healing process can’t tolerable. The present study was aimed to investigate the anti-inflammatory activit...

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ژورنال

عنوان ژورنال: BMC Infectious Diseases

سال: 2012

ISSN: 1471-2334

DOI: 10.1186/1471-2334-12-s1-p90